How does stomach cancer relate to the cell cycle?
Answers
Answer:
Cancer is uncontrolled division of cells, or in other words, a disease of the cell cycle.
Explanation:
When stomach cells become cancerous and divide rapidly, it is most likely a cell cycle issue.
During the cell cycle, "checkpoints" exist to ensure that a cell divides when it is supposed to. For instance, checkpoints make sure that
all the genetic code (DNA) has been replicated accurately in a cell
chromosomes are lined up properly at the middle of the cell during metaphase
spindle fibers or properly attached to the chromosomes
before cell division begins.
When cancer occurs, it could be a result of positive regulators being over-activated or cell cycle inhibitors being inactivated . Changes in cell cycle activity and inhibitors/regulators are due to mutations in the genetic code of the proteins.
Additionally, when a normal cell becomes damaged, the cell cycle usually forces the cell to undergo apoptosis, or programmed cell death. Cancer cells manage to avoid this cell death.