How genetic recombination is helpful in microbiology?
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DNA recombination involves the exchange of genetic material either between multiple chromosomes or between different regions of the same chromosome. This process is generally mediated by homology; that is, homologous regions of chromosomes line up in preparation for exchange, and some degree of sequence identity is required. Various cases of nonhomologous recombination do exist, however.
One important instance of recombination in diploideukaryotic organisms is the exchange of genetic information between newly duplicated chromosomes during the process of meiosis. In this instance, the outcome of recombination is to ensure that each gamete includes both maternally and paternally derived genetic information, such that the resulting offspring will inherit genes from all four of its grandparents, thereby acquiring a maximum amount of genetic diversity. Recombination is also used in DNA repair (particularly in the repair of double-stranded breaks), as well as during DNA replication to assist in filling gaps and preventing stalling of the replication fork. In these cases, a sister chromatid serves as the donor of missing material via recombination followed by DNA synthesis.
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your answer is below...
DNA recombination involves the exchange of genetic material either between multiple chromosomes or between different regions of the same chromosome. This process is generally mediated by homology; that is, homologous regions of chromosomes line up in preparation for exchange, and some degree of sequence identity is required. Various cases of nonhomologous recombination do exist, however.
One important instance of recombination in diploideukaryotic organisms is the exchange of genetic information between newly duplicated chromosomes during the process of meiosis. In this instance, the outcome of recombination is to ensure that each gamete includes both maternally and paternally derived genetic information, such that the resulting offspring will inherit genes from all four of its grandparents, thereby acquiring a maximum amount of genetic diversity. Recombination is also used in DNA repair (particularly in the repair of double-stranded breaks), as well as during DNA replication to assist in filling gaps and preventing stalling of the replication fork. In these cases, a sister chromatid serves as the donor of missing material via recombination followed by DNA synthesis.
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