How hox genes are regulated by trithorax and polycomb proteins in drosophila?
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These two groups of genes were discovered in Drosophila by their opposing effects on homeotic gene (Hox) expression. PcG genes collectively behave as genetic repressors of Hox genes, while the TrxG genes are necessary for HOX gene expression or function. ... TrxG proteins activate transcription via a variety of mechanisms.
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