How is bile pigment removed from our body?
Answers
Answer:
Elimination of heme is accomplished in a series of steps:
Free bilirubin is stripped off albumin and absorbed by - you guessed it - hepatocytes. ... Conjugated bilirubin is secreted into the bilecanaliculus as part of bile and thus delivered to the small intestine.
The excretion of Bile pigment in the body occurs through following steps:
1) Bile pigments are the pigments broken down from haem protein of circulating RBC's in the blood.
2) Liver takes up this broken pigments and forms conjugated bilirubin by attaching it with sulphate or glucuronic acid.
3) This conjugated bilirubin passes to the small intestine through bile canaliculus.
4) Due to the presence of many gut bacteria, this conjugated bilirubin is ultimately metabolised into other components which are finally eliminated through urine or stool.