Question

How is endothelil dysfunction induced in huvec cells?

Answer 1

Culture of ECs was first reported nearly four decades ago [10] and until recently, the progress in the knowledge of endothelial physiology has been mainly the consequence of investigations performed with ECs in culture. Due to the limited availability of human vascular endothelial tissue, EC functions have been modified in cell culture to mimic alterations of vascular wall properties as a relevant experimental model in understanding endothelial physiology and the study of the interaction of ECs with blood cells and various mediators.