How is Glomerulus different from the network of capillaries that surrounds alveoli in lungs?
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glomerulus helps in extracting the components of blood and moves them in PCT for absorption
alveoli in lungs is used for diffusion of o2 and co2
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The capillary network in the lung and other organs has been extensively studied. Capillaries range from 2 to 8 μm in diameter (Doerschuk, et al., 1993). Average neutrophil diameter has been variously estimated (by electron microscopy) at 6.8 μm (Doerschuk, et al., 1993) and 8.5 μm (Shao, et al., 1998). Most leukocytes must thus undergo considerable deformation on entering capillaries. There are two competing models for the geometry of alveolar capillary beds in the lung (Dawson and Linehan, 1997). One classic model treats the bed as a pair of parallel plates with posts (perhaps at high density) that run between the plates (Sobin and Fung, 1992). An alternate view is that the alveolar capillary bed is more tubelike (Guntheroth, et al., 1982). An electron micrograph of a latex cast of the rat lung microcirculation that demonstrates the latter geometry is reproduced.
In this latter tubule geometry, relatively straight capillary segments connect with other capillaries and branch off again. at the “vestibules” where vessels bifurcate, vessel diameters are significantly larger than in the straighter segments. The vestibules then branch and taper down again into a few exit vessels within a cell diameter or so. Mechanical arrest has been observed both in junction regions (where capillaries taper significantly) and in straight segments (where there is little tapering) (Gebb, et al., 1995). The degree of tapering in capillary networks varies, but it is estimated that diameter can change from 8 to 4 μm within one or two cell diameters (8–16 μm) (Bathe, et al., 2002; Guntheroth, et al., 1982).
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