How is pyruvate broken down in the absence of oxygen?
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When oxygen is not present, pyruvate will undergo a process called fermentation. In the process of fermentation the NADH + H+ from glycolysis will be recycled back to NAD+ so that glycolysis can continue. In the process of glycolysis, NAD+ is reduced to form NADH + H+.
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ᴡʜᴇɴ ᴏxyɢᴇɴ ɪꜱ ɴᴏᴛ ᴩʀᴇꜱᴇɴᴛ, ᴩyʀᴜᴠᴀᴛᴇ ᴡɪʟʟ ᴜɴᴅᴇʀɢᴏ ᴀ ᴩʀᴏᴄᴇꜱꜱ ᴄᴀʟʟᴇᴅ ꜰᴇʀᴍᴇɴᴛᴀᴛɪᴏɴ. ɪɴ ᴛʜᴇ ᴩʀᴏᴄᴇꜱꜱ ᴏꜰ ꜰᴇʀᴍᴇɴᴛᴀᴛɪᴏɴ ᴛʜᴇ ɴᴀᴅʜ + ʜ+ ꜰʀᴏᴍ ɢʟyᴄᴏʟyꜱɪꜱ ᴡɪʟʟ ʙᴇ ʀᴇᴄyᴄʟᴇᴅ ʙᴀᴄᴋ ᴛᴏ ɴᴀᴅ+ ꜱᴏ ᴛʜᴀᴛ ɢʟyᴄᴏʟyꜱɪꜱ ᴄᴀɴ ᴄᴏɴᴛɪɴᴜᴇ. ɪɴ ᴛʜᴇ ᴩʀᴏᴄᴇꜱꜱ ᴏꜰ ɢʟyᴄᴏʟyꜱɪꜱ, ɴᴀᴅ+ ɪꜱ ʀᴇᴅᴜᴄᴇᴅ ᴛᴏ ꜰᴏʀᴍ ɴᴀᴅʜ + ʜ+.
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