How LOD scores are used to test linkage of genes?
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LOD score, or logarithm of odds score, is a statistical test used in genetic linkage analysis. The LOD score compares the probability of obtaining the test data if the two loci are linked to the probability of obtaining the test data if the two loci are not linked
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The statistical method of linkage analysis combines these data to identify chromosome regions likely to harbor genes for the trait. Parametric linkage analysis is used for traits with a Mendelian form of inheritance. LOD scores and recombination fractions are used to test the gene locations.
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