How many ATP produced in hmp pathway?
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Answer- The pentose phosphate pathway (also called
Phospho gluconate pathway or hexose monophosphate
shunt [HMP shunt]) is an alternative route for the
metabolism of glucose. It does not lead to formation of
ATP but has two major functions: (1) The formation of
NADPH for synthesis of fatty acids and steroids, and (2)
the synthesis of ribose for nucleotide and nucleic acid
formation
Overview of HMP pathway
The pentose phosphate pathway meets the need of all
organisms for a source of NADPH to use in reductive
biosynthesis .This pathway consists of two phases: the
oxidative generation of NADPH and the nonoxidative
interconversion of sugars (Figure 1). In the oxidative
phase, NADPH is generated when glucose 6-phosphate
is oxidized to ribose 5-phosphate. This five-carbon sugar
and its derivatives are components of RNA and DNA, as
well as ATP, NADH, FAD, and coenzyme A
Glucose 6-phosphate 2 NADP H2O
ribose 5-phosphate 2 NADPH2H
CO
In the nonoxidative phase, the pathway catalyzes the
interconversion of three-, four-, five-, six-, and seven-
carbon sugars in a series of nonoxidative reactions that
can result in the synthesis of five-carbon sugars for
nucleotide biosvnthesis or the conversion of excess five-
carbon sugars into intermediates of the glycolytic
pathway. All these reactions take place in the cytosol
Phospho gluconate pathway or hexose monophosphate
shunt [HMP shunt]) is an alternative route for the
metabolism of glucose. It does not lead to formation of
ATP but has two major functions: (1) The formation of
NADPH for synthesis of fatty acids and steroids, and (2)
the synthesis of ribose for nucleotide and nucleic acid
formation
Overview of HMP pathway
The pentose phosphate pathway meets the need of all
organisms for a source of NADPH to use in reductive
biosynthesis .This pathway consists of two phases: the
oxidative generation of NADPH and the nonoxidative
interconversion of sugars (Figure 1). In the oxidative
phase, NADPH is generated when glucose 6-phosphate
is oxidized to ribose 5-phosphate. This five-carbon sugar
and its derivatives are components of RNA and DNA, as
well as ATP, NADH, FAD, and coenzyme A
Glucose 6-phosphate 2 NADP H2O
ribose 5-phosphate 2 NADPH2H
CO
In the nonoxidative phase, the pathway catalyzes the
interconversion of three-, four-, five-, six-, and seven-
carbon sugars in a series of nonoxidative reactions that
can result in the synthesis of five-carbon sugars for
nucleotide biosvnthesis or the conversion of excess five-
carbon sugars into intermediates of the glycolytic
pathway. All these reactions take place in the cytosol
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