How many proteins of average size could be encoded in a virus with a dna genome having 12,000 bp, assuming no overlap of genes?
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Answer:
2,134 proteins of average size could be encoded in a virus with a dna genome having 12,000 BP, assuming no overlap of genes.
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Solution:
10 proteins of the average size of 400bs will be synthesized.
Explanation:
- If the virus genome is of size 12000 bp and there is no overlap of genes.
- The average size of protein in a virus can be 400 amino acids.
- Each codon has 3 base pairs and each codon will synthesis for 1 amino acid that has 3 nucleotides or base pairs.
- For average-sized protein of 400 amino acids will require 400 codons means 1200 base pairs (3×400).
- Hence, the total number of proteins synthesized is the total size of the genome in base pair ÷ size of protein in base pair
- =12000÷1200
- =10 proteins
A 400 aa sized protein will need 400 codons = 3 x 400 = 1200 bp
Hence the total number of proteins that can be made is,
Total size of genome in bp/Size of 1 protein in bp = 12000/1200 = 10
The answer is 10 proteins of average length 400 aa.
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