how many times the adult human produces the urine more concentrated than the henles loop
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The longer the loop of Henle relative to the overall depth of the cortex, the higher is the osmolarity of the fluid in the bend. The kidney thereby retains as much water as possible, minimising loss of water during water shortage.
The 300 mOsm/L fluid from the loop loses water to the higher concentration outside the loop and increases in tonicity until it reaches its maximum at the bottom of the loop. This area represents the highest concentration in the nephron, but the collecting duct can reach this same tonicity with maximum ADH effect.
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human body can produce 4times urine concentrated
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