Question

how morphine cause euphoria even its receptor are inhibitory in nature​

Answer 1

Answer:

Organ system effects of morphine and its surrogates. ... and cause activation of central dopamine reward pathways that modulate euphoria. ... however, may not be due to opioid receptor uncoupling from inhibitory G- proteins

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Answer 2

Opioids are a group of analgesic agents commonly used in clinical practice. There are three classical opioid receptors (DOP, KOP and MOP), while the novel NOP receptor is considered to be a non-opioid branch of the opioid receptor family. Opioids can act at these receptors as agonists, antagonists or partial agonists.