Question

How penicilline g gets deactivated under acidic ph?

Answer 1

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A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.

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Answer 2

$\boxed{Explained\:Answer}$

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■ A series of α-substituted benzyl penicillins (I) in the hope of finding an acid-stable penicillinactive against Gram-negative as well as Gram-positive bacteria.

■ It is effective against most gram-positive bacteria and against gram-negative cocci.