Question

How the bacteria produce insulin in human?

Answer 1

When the bacterium reproduces, the insulin gene is replicated along with the plasmida circular section of DNA. E. coli produces enzymes that rapidly degrade foreign proteins such as insulin. By using mutant strains that lack these enzymes, the problem is avoided. E. coli, B-galactosidase is the enzyme that controls the transcription of the genes. To make the bacteria produce insulin, the insulin gene needs to be tied to this enzyme.