How the stomach protect itself from the harmful hydrochloric acid secreted by gastric glands?
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In the stomach several mucosal defence mechanisms protect the stomach against hydrochloric acid and noxious agents. The pre-epithelial protection is made up by the mucus-bicarbonate barrier. Mucus and bicarbonate, secreted by mucus cells, create a pH gradient maintaining the epithelial cell surface at near neutral pH.
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HYDROCHLORIC ACID SECRETED BY GASTRIC GLANDS
- In the stomach several mucosal defence mechanism protect the stomach against hydrochloric acid and noxious agents.
- The pre-epithelial protection is made up by the mucus -bicarbonate barrier.
- Mucus and bicarbonate, secreted by mucus cells, create a pH gradient maintaining the epithelial cell surface at near neutral pH.
- Stomach protects itself from being digested by its own enzymes , or burnt by the corrosive hydrochloric acid , by secreting sticky, neutralising mucus that clings to the stomach walls.
- Both the cardiac and pyloric glands secrete mucus ,which coats the stomach and protect it from self-digestion by helping to dilute acids and enzymes.
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