Question

How to calculate genetic distance between families in mega?

Answer 1

In MEGA or anyother program you are using for calculating genetic distances you'll need a Multiple Sequence Alignment file......If you are planning to calculate the distance or divregence for each gene separately you'll need two separate alignment files....this would be also useful to study the relative divergences and evolution of the two sequences among the taxa of your interest......for inferring pyholgenetic relationships you can use information from both the sequences separately or collectively ...using concatenated aligned sequences and then proceeding forward using MEGA.....or anyother program
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