Question

How to calculate in patients statistics with carry forward?

Answer 1

Drug trials are designed to follow patients over time to determine the effect of the study drug. Participants often drop out before study completion. If these dropouts are not included in analyses, randomized trials can generate false results. Consequently, intention-to-treat analysis — the inclusion of all participants in the analysis according to the group determined at randomization — has become the standard for controlled trials. As part of this analysis, methods are used to estimate the missing data for patients who have dropped out.


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Answer 2

Answer:

Last observation carried forward (LOCF) is a method of imputing missing data in longitudinal studies. If a person drops out ...