Question

how to use Tf2O in organic chemistry, ​

Answer 1

Answer:

Triflic anhydride is the chemical compound with the formula (CF3SO2)2O. It is the acid anhydride derived from triflic acid. This compound is a strong electrophile, useful for introducing the triflyl group, CF3SO2. Abbreviated Tf2O, triflic anhydride is the acid anhydride of the strong acid triflic acid, CF3SO2OH.

Triflic anhydride is useful for converting ketones into enol triflates.

In a representative application, is used to convert an imine into a NTf group.[5] It will convert phenols into a triflic ester, which enables cleavage of the C-O bond

Answer 2

Answer:

Triflic anhydride with formula (CF3SO2)20, is acid-based anhydride of Triflic acid.

Its uses in organic chemistry are:

1. useful for converting ketones into enol triflates.
2. useful in converting an imine into a NTf group.
3. useful in converting phenols into a triflic ester, which enables cleavage of the C-O bond.

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