Human immunodeficiency virus structure,virus entry,replication
Answers
Explanation:
HIV uses a complex series of steps to deliver its genome into the host cell cytoplasm while simultaneously evading the host immune response. To infect cells, the HIV protein envelope (Env) binds to the primary cellular receptor CD4 and then to a cellular coreceptor. This sequential binding triggers fusion of the viral and host cell membranes, initiating infection. Revealing the mechanism of HIV entry has profound implications for viral tropism, transmission, pathogenesis, and therapeutic intervention
Answer: The HIV replicates in the host by a process of reverse transcription, In this process the viral RNA replicates to form viral DNA then gets incorporated into the host cells’s DNA which directs the infected cell to produce virus particles.
