Huntington chorea has which deficiency of which amino acids
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Answer:
One of the ways the body makes cysteine and hydrogen sulfide is through the activity of a protein called cystathionine gamma-lyase (CSE). To study the role of hydrogen sulfide in the body, Snyder’s team made a mouse that lacked the gene that tells cells how to make the CSE protein. This so-called knockout mouse approach is a common way to study the function of genes in the lab - just get rid of them and then see what happens to the resulting animals.
When suspended by their tails, mice that lacked the CSE gene made a very funny clasping motion - bringing all four of their limbs in towards their body. A number of mice with brain problems, including some HD mice, make this same strange clasping motion. It reminded Snyder’s group so much of HD mice that they decided to see if there was any connection between the activity of CSE and HD.
Woody Guthrie
Like amyotrophic lateral sclerosis (ALS), it is a degenerative neurological disorder. Like ALS, whose eponymous sufferer was baseball player Lou Gehrig, Huntington's has a famous victim — the folk singer Woody Guthrie, who died in 1967. Both diseases proceed unabated once their symptoms appear.