Identification of granulocytes and agranulocytes with function
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Agranulocytes are the white blood cells with one lobed nucleus and do not consist of granular system whereas granulocytes consists of a granular cytoplasm
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Lymphocytes is classified into two types granulocytes and agranulocytes on the basis of the presence of granular cytoplasm and their functions.
The granulocytes have 72% of total white blood cells and have granular cytoplasm. They originate in bone marrow.
They are mainly involved in innate immune mechanisms. They have polylobed nucleus.
The agranulocytes have 28% of total white blood cells and the cytoplasm of a granulocytes does not contain any granules. They originate from bone marrow and lymph nodes. They are involved in adaptive immune mechanisms. They have single lobed nucleus.
The granulocytes contains Eosinophils, Basophils and Neutrophils.
- Eosinophils are present in about 1 to 6% of WBC count or 105/mm³ of blood. They have bilobed nucleus. They have antihistamine properties.
- Basophils are present in about 0 to 1% of WBC count or 35/mm³ of blood. They have multilobed nucleus, often S shaped nucleus. They produce histamine and heparin.
- Neutrophils are present in about 42 to 75% of WBC count or 4900/mm³ of blood. The nucleus is multilobed. They engulf bacteria.
The agranulocytes contains monocytes and lymphocytes.
- The monocytes are present in about 4% of WBC count or 280/mm³ of blood. They have bean shaped nucleus. They are involved in engulfing bacteria and are phagocytic in nature.
- Lymphocytes Al present in about 24 percent of WBC count or 1680/mm³ of blood. They have large shaped oval nucleus. They produce antibodies and phagocytic in nature.
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