Identification of hydroxylated pcb metabolites and other phenolic halogenated pollutants in human blood plasma
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If drugs are biotransferred to more reactive metabolites why would enzyme induction cause drug induced tissue toxicity
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☑️ A growing number of studies have reported phenolic halogenated compounds (PHCs) that are retained in the blood of humans and wildlife. These PHCs may be industrial chemicals; metabolites thereof, as in the case with polychlorobiphenylols (OH-PCBs); or of natural origin.
The present study was aimed to identify hitherto unknown PHCs in human plasma with chemical structures that are consistent to PHCs known to possess endocrine-disrupting activity.
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