Identify the incorrect statement a) In a Thalassemia, production of globin chain is affected while in Thalassemia, production of B globin chain is affected. b) B Thalassemia is more frequent in a population than a Thalassemia. c. ß Thalassemia is controlled by two closely linked genes HBA1 and HBA2 on chromosome 16 of each parent while a Thalassemia is controlled by a single gene HBB on chromosome 11. d) Thalassemia is an autosome-linked recessive blood disease transmitted from parents to the offspring when both the partners are unaffected and carrier for the gene (or heterozygous).
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The HBA2 gene provides instructions for making a protein called alpha-globin. This protein is also produced from a nearly identical gene called HBA1. These two alpha-globin genes are located close together in a region of chromosome 16 known as the alpha-globin locus.
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