If 9% (i.e. q2) of an African population is born with a severe sickle cell anemia, what percentage of population (i.e. 2 pq) will be more resistant to malaria because they are heterozygous for sickle cell gene?
Options: (a) 0.3% (b) 0.7% (c) 42% (d) 210%
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Answer: (c) 42%
Explanation:
q2 = 9%
q = √9/100 = 3/10
q = 0.3
p + q = 1
p = 1 – q
= 1 – 0.3 = 0.7
2pq = 2 × 0.3 × 0.7
= 0.42
2pq = 42%
42% of individuals would be resistant to malaria.
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