Question

if drug is soluble in less than one part as per IP it is designated as​

Answer 1

Answer:

Solubility is based on the highest-dose strength of an immediate release product. A drug is considered highly soluble when the highest dose strength is soluble in 250 mL or less of aqueous media over the pH range of 1 to 7.5.

Answer 2

Answer:

If the drug is soluble in less than one part as per IP then it is designated as a very or highly soluble drug.

Explanation:

• Increasing the solubility is the most significant factor in the formulation development of the drug.
• Solubility is one of the important properties to gain desired concentration of a drug in systemic circulation to show pharmacological response.
• It is essential to increase or improve the solubility and dissolution rate, especially for poorly soluble drugs. As these drugs have low absorption and bioavailability.
• Find the IP solubility table attached below.