if non disfunction of chromosome 21 is known to occur in division of secondary oocyte in a particular women then what is the chance that a mature egg arising from this cell division will receive 21 chromosomes
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Down syndrome (trisomy 21)
The majority of cases result from nondisjunction during maternal meiosis I. Trisomy occurs in at least 0.3% of newborns and in nearly 25% of spontaneous abortions. It is the leading cause of pregnancy wastage and is the most common known cause of mental retardation.
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