Question

If one parent belongs to 'A' blood group and the other to 'O' blood group, their children possibly represent [CPMT 1973]
A) A and B groups only
B) AB only
C) A and O groups only
D) All four groups

Answer 1

If one parent belongs to 'A' blood group and the other to 'O' blood group, their children possibly represent [CPMT 1973]
A) A and B groups only
B) AB only
C) A and O groups only◀◀◀
D) All four groups

Answer 2

Their children can represent C) A and O groups only.

1. The blood group O has alleles ii and the blood group A has alleles ia and ia or Ia and i.
2. In a given situation the combination of blood groups after cross-over can contain alleles Ia and/or i.
3. Thus, the resultant blood group can only be A and O.
4. The blood group B has alleles Ib and i or Ib and Ib.
5. The blood group AB has alleles Ia and Ib.
6. Now, since the child can not inherit the Ib blood group, thus, blood groups B and AB are not possible.
7. When a blood group has a particular antigen eg. A, it has antibodies against the other antigens eg. B. Hence, transfusion of incompatible blood will cause antigen-antibody interaction.
8. This results in an attack on foreign Red blood cells by the immune system further causing issues to health.

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