if the organization of a cell is destroyed due to some physical or chemical influence ,what wi happen?
Answers
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Cell death is a vital and common occurrence. In humans, some 10 billion new cells may form and an equal number die in a single day. Biologists recognize two general categories of cell death, which include genetically programmed death and death resulting from external forces (necrosis).
Necrosis is our topic so…
Cells die in an unplanned manner when exposed to a variety of harmful environmental agents. These include both chemical and physical events, or “insults,” and range from radiation, heat, toxic substances, bodily trauma or injury and lack of oxygen. Injured cells swell up, burst, spill their contents and cause surrounding cells to react defensively. This often involves inflammation and the calling in of specialized immune cells to deal with cleanup and isolation of the damaged tissue.
This immune response cleans the cell debris.
This initiates in the surrounding tissue an inflammatory response which attracts leukocytes and nearby phagocytes which eliminate the dead cells by phagocytosis. However, microbial damaging substances released by leukocytes would create collateral damage to surrounding tissues. This excess collateral damage inhibits the healing process. Thus, untreated necrosis results in a build-up of decomposing dead tissue and cell debris at or near the site of the cell death. A classic example is gangrene. For this reason, it is often necessary to remove necrotic tissue surgically, a procedure known as debridement.
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