Chemistry, asked by vishalhkoli1198, 1 day ago

ii) Conversion of PhCHMe CO2H to PhCHMe NH2 iii) Reaction of ketoximetosylate with ethoxide ion.​

Answers

Answered by samruddhidesai3
1

The oxime is first converted to an O-sulfonate, for example a tosylate by reaction with tosyl chloride. Added base forms a carbanion which displaces the tosylate group in a nucleophilic displacement to an azirine and added water subsequently hydrolyses it to the aminoketone.

The Beckmann rearrangement is a side reaction.

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