In 1000101010 the least significant bit is
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In computer science and information theory, a bit is the smallest possible meaningful piece of information. It is most often expressed as a digit of the binary numeral system: either 0 or 1. A string of 8 bits is called a byte.
If we take, for example, the binary number 11100111 (231 in decimal), and send it as a string of data of a network, we can send it in two ways: starting from left to right, or starting right to left. These two orderings are commonly called Most Significant Bit First, and Least Significant Bit First, respectively.
In this case, we referred to the first, or left-most bit as the Most Significant Bit (msb for short). The msb is the bit in a binary sequence that carries the greatest numerical value. For simpler reference, if we take a look at the equivalent decimal number, 231, the most significant digit is the leading 2. Compared to the other two digits, the leading 2 determines the greatest part of the number's numerical value, as it signifies the hundreds in the number. Analogous to this, the leading 1 in our binary number is it's most significant bit.