In a variant of chymotrypsin, Asp 102 is replaced by Glu 102 Do you expect the enzyme to retain activity? Schematically indicate the role of amino acid residues participating in catalysis
Answers
Answered by
1
Answer:
Negatively charged Asp 102 partially borrow hydrogen ion from His-57. His-57 attracts hydrogen ion from adjacent Ser 195 Serine 195 gets negative charge. Serine 195 makes a nucleophilic attack on the protein substrate.
Explanation:
Similar questions