In descending limb of loop of Henle, filtrate becomes
(1) Hypotonic to plasma
(2) Isotonic to plasma
(3) Hypertonic to plasma
(4) Isotonic to lymph
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Explanation:
The thin descending limb has low permeability to ions and urea, while being highly permeable to water. The loop has a sharp bend in the renal medulla going from descending to ascending thin limb. The thick ascending limb is impermeable to water, but it is permeable to ions.
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