In gene mutations when a purine is substituted by another purine it is called as
(A) Transformation
(B)
Translocation
(C) Transduction
(D) Transition
B
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Explanation:
In genetics, a transition is a point mutation that changes a purine nucleotide to another purine (A-G) or a pyrimidine nucleotide to another pyrimidine (C-T).
Transitions can be caused by oxidative deamination and tautomerization. Although, there are twice as many possible transversions, transitions appear more often in genomes, possibly due to the molecular mechanisms that generate them. 5-Methylcytosine is more prone to transition than unmethylated cytosine, due to spontaneous deamination. This mechanism is important because it dictates the rarity of CpG islands.
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The answer is B
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