In humans the sulphur of methionine and cysteine is excreted mainly as
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End-product sulfur (S) arises predominantly from the catabolism of the sulfur amino acids (SAA) methionine and cysteine. Sulfate and taurine are the two main S-containing end products and, once formed, they are excreted almost entirely in the urine (10–14).
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In humans, the sulphur of methionine and cysteine is excreted mainly as an inorganic sulfate(urine).
Explanation:
- Inorganic sulfate is an essential and ubiquitous anion in human biology, but it is rarely studied in clinical chemistry today.
- Urinary excretion is the major disposal mechanism for excess sulfate produced by the oxidation of sulfur amino acids, and the kidney is the major regulatory site.
- Sulfate is a major urinary anion that has a significant affinity for cations and regulates the availability of cations that react with other anions in the urine.
- Therefore, it is an important factor in the urinary supersaturation of various crystals and stones such as calcium oxalate, hydroxyapatite, and blush stones.
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