in one compartment open model , absorption rate constant can be calculated by
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Answer:
For a medication that is absorbed in the body in a first-order manner, distributed in the body using one-compartment kinetics, and then removed in a first-order manner.
Explanation:
- The differential form of the equation is:
dx/dt = Ka Xa- Ke X
where,
Ka = first-order absorption rate constant, and
Xa = amount of drug at the absorption site remaining to be absorbed.
- The residuals approach can be used to calculate the absorption rate constant.
- The method is additionally referred to as feathering, peeling, and stripping.
- The process of breaking down a multiexponential curve into its component parts is frequently employed in pharmacokinetics.
- When a drug is delivered intravenously and follows one-compartment kinetics, the amount of drug in the plasma.
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