In prokaryotes during tranacription the if2 binds to
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Prokaryotic initiation factor-2 is a prokaryotic initiation factor. IF2 binds to an initiator tRNA and controls the entry of tRNA onto the ribosome. ... When the 50S subunit joins, it hydrolyzes GTP to GDP and Pi, causing a conformational change in the IF2 that causes IF2 to release and allow the 70S ribosome to form.
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