Question

In the context of recent advances in human reproductive technology, "Pronuclear

Transfer" is used for


(a) fertilization of egg in vitro by the donor sperm

(b) genetic modification of sperm producing cells

(c) development of stem cells into functional embryos

(d) prevention of mitochondrial diseases in offspring

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Answer 1

Answer:

The answer is (a) fertilization of egg in vitro by the donor sperm

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Answer 2

Answer:

Ans-(d) prevention of mitochondrial diseases in offspring

Explanation:

• A pronucleus is the nucleus of the egg or sperm at the stage of fertilization prior to nucleus fusion.
• A pronuclear transfer is used in the process of a three-parent baby.
• In the process the mother’s egg is first fertilized with the father’s sperm, producing a zygote. The pro-nuclei of the egg and sperm are then removed from the zygote and inserted into a donor egg that has been fertilized and has had its own nucleus removed. The zygote derived from the donor egg is then implanted into the mother’s uterus.
• The reproductive technologies used to produce three-parent babies focus on reducing the effects of mutations that occur in the DNA of cellular organelles known as mitochondria, which reside in the cell cytoplasm.