Question

In the first step of fatty acid biosynthesis, the carboxylation of acetyl CoA to fom malonyl CoA is catalyzed by the enzyme acetyl CoA carboxylase, that has _______ as a cofactor.

Answer 1

Acetyl CoA carboxylase plays an essential role in regulating fatty acid synthesis and degradation. Recall that this enzyme catalyzes the committed step in fatty acid synthesis: the production of malonyl CoA (the activated two-carbon donor).