In the pathogenesis of acute respiratory failure in anaphylactic shock there is
bronchospasm, mucus hypersecretion, edema of the mucous membrane of the
lower respiratory tract. Which of the mediators determine the development of
these disorders:
1 Heparin, serotonin
2 Kinins
3 Interleukins 1, 2
4 Complement proteins
5 Histamine, leukotrienes
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High-molecular heparin-serotonin complex (3:1 weight ratio) was obtained in vitro. The complex, its components, and heparin-serotonin mixture were introduced intraperitoneally in rats, and the resulting effects were registered 10, 30, and 60 min later
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