Increase of solubility of drug in water in presence of additives is known as
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Answer:
Increase of solubility of drug in water in presence of additives is known as
super saturated solution
Explanation:
By heating a saturated solution, adding an additional solute, and then gradually cooling it, one can create a supersaturated solution, which has more dissolved solute than needed to create a saturated solution. By introducing a small number of the solute crystals into the supersaturated solution, extra dissolved solute crystallises.
application of supersaturated solution
- A solution of a solid solute dissolved in a liquid solvent is in thermodynamic equilibrium when it reaches saturation.
- The system must move into a nonequilibrium state, where the concentration of the solute in the solution exceeds its equilibrium concentration under the specified solution conditions, for crystallisation to take place.
- Supersaturated solutions are those that exist in the nonequilibrium state. Cooling is the most straightforward way to produce a supersaturated solution.
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