Question

Indicate which nitrogen compound amongst the
following would undergo Hofmann reaction (i.e..,
reaction with Br₂ and strong KOH) to furnish
the primary amine (R – NH₂)
(a) RCONHCH₃
(b) RCOONH₄
(c) RCONH₂
(d) R - CO- NHOH.

Answer 1

Answer:

Explanation:

(d) R - CO- NHOH

Answer 2

(c) RCONH₂

Explanation:

Amides give Hofmann bromamide reaction. Reaction of RCONH2 with a mixture of Br2 and KOH gives RNH2 as the main product.  When an amide is treated with bromine in an aqueous or ethanolic solution of sodium hydroxide, degradation of amide takes place leading to the formation of primary amine. This reaction involving degradation of amide is popularly known as Hoffmann bromamide degradation reaction.

Option C is the answer.