Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds.
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Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Danwei Huangfu ; , René Maehr; , Wenjun Guo; , Astrid ...
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Abstract. Reprogramming of mouse and human somatic cells can be achieved by ectopic expression of transcription factors, but with low efficiencies. ... VPA also enables efficient induction of pluripotent stem cells without introduction of the oncogene c-Myc.
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