Inflammatory response in allergy is due to release by mast cells of
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It usually recovers within 2-4 hours. Mast cells also have a large role in allergic reactions as IgE specific antibodies for antigens inhabit these cells following sensitisation. ... This leads to mast cell degranulation (rupture) and the release of inflammatory mediators.
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Mast cells are now considered to be part of the immune system. ... They are able to release potentinflammatory mediators, such ashistamine, proteases, chemotactic factors, cytokines and metabolites of arachidonic acid that act on the vasculature, smooth muscle, connective tissue, mucous glands andinflammatory cells.
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