insoluble powder and oily preparation in
Answers
Answer:
Types of dosage forms: Definition: Dosage forms are the means by which drug molecules are delivered to sites of action within the body. The need for dosage forms: 1- Accurate dose. 2- Protection e.g. coated tablets, sealed ampules. 3- Protection from gastric juice. 4- Masking taste and odour. 5- Placement of drugs within body tissues. 6- Sustained release medication. 7- Controlled release medication. 8- Optimal drug action. 9- Insertion of drugs into body cavities (rectal, vaginal) 10- Use of desired vehicle for insoluble drugs.
3. They are classified according to: Route of administration Physical form Oral Solid Topical Semisolid Rectal liquid Parenteral Vaginal Inhaled Ophthalmic Otic Types of dosage forms (Cont.):
4. Oral dosage forms: 1-Tablet: A tablet is a hard, compressed medication in round, oval or square shape. The excipients include: -Binders, glidants (flow aids) and lubricants to ensure efficient tabletting. -Disintegrants to ensure that the tablet breaks up in the digestive tract. -Sweeteners or flavours to mask the taste of bad-tasting active ingredients. -Pigments to make uncoated tablets visually attractive. .
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6. 1-Tablet (Cont.) A coating may be applied to: 1- hide the taste of the tablet's components. 2- make the tablet smoother and easier to swallow . 3- make it more resistant to the environment. 4- extending its shelf life.
7. 2-Buccal and sublingual tablet: - Sublingual and buccal medications are administered by placing them in the mouth, either under the tongue (sublingual) or between the gum and the cheek (buccal). - The medications dissolve rapidly and are absorbed through the mucous membranes of the mouth, where they enter into the bloodstream. - Avoid the acid and enzymatic environment of the stomach and the drug metabolizing enzymes of the liver. - Examples of drugs administered by this route: e.g. vasodilators, steroidal hormones.
8. 3-Effervescent tablet: Effervescent tablets are uncoated tablets that generally contain acid substances (citric and tartaric acids) and carbonates or bicarbonates and which react rapidly in the presence of water by releasing carbon dioxide. -They are intended to be dissolved or dispersed in water before use providing: A- Very rapid tablet dispersion and dissolution. B- pleasant tasting carbonated drink.
Explanation:
Answer:
Typically, insoluble granules are employed as capsule filler. Essential oils and other greasy preparations can also be placed inside of capsules for simpler administration.
Explanation:
What use do greasy and insoluble formulations serve in capsules?
- Powders known as insoluble solids are incapable of dissolving in a liquid. Powders that are insoluble include talc, alumina, and several inorganic salts.
- Typically, the insoluble powder is utilised as an extender or filler in a variety of pharmacological compositions.
- One kind of capsule formulation used to deliver lipophilic medications and other components is oily preparations in capsules.
- A lipophilic outer shell plus a lipophilic core holding the active component make up these capsules.
- The active ingredient is released into the bloodstream as the capsules swiftly breakdown in the digestive system.
- There are various benefits to using oily and insoluble powders in capsules. First off, administering these preparations is quick and simple.
- For a variety of uses, oily formulations in capsule form as well as insoluble powders have been employed.
- In pharmaceutical compositions, insoluble powders are frequently employed as fillers or extenders. Lipophilic medications are delivered by oily formulations in pill form.
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(Complete Question : what is the use of insoluble powders and oily preparations in capsules ?)