intrinsic and extrinsic process of clotting. (Distinguish)
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The intrinsic pathway is activated through exposed endothelial collagen, and the extrinsic pathway is activated through tissue factor released by endothelial cells after external damage. This pathway is the longer pathway of secondary hemostasis. ... Endothelial collagen is only exposed when endothelial damage occurs.
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Anss- Intrinsic -
The intrinsic pathway requires only clotting factors found within the blood itself - in particular, clotting factor XII (Hageman factor) from the platelets.
Extrinsic -
The extrinsic pathway is initiated by factors external to the blood, in the tissues adjacent to a damaged blood vessels.
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