Question

Ionic group of detergent

Answer 1

Ionic detergents have a hydrophilic head group that is charged and can be either negatively (anionic) or positively (cationic) charged. Ionic detergents are used for the complete disruption of cellular structures and denaturation of proteins for separation during gel electrophoresis.

Ionic Detergents For Protein


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Answer 2

The polar head group of ionic detergents contain either a positive (cationic) or negative (anionic) charge.  Anionic detergents typically have negatively-charged sulfate groups as the hydrophilic head; whereas cationic detergents contain a positively-charged ammonium group. They are frequently used for common household soaps and cleansers, but can also serve specific purposes in a lab setting.  Ionic detergents have stronger effects than uncharged detergents, because they bind to protein molecules, altering the protein’s charge and structure. They should be used when the preferred outcome involves modifying proteins and disrupting cellular structures, such as in gel electrophoresis.