Is it possible to predict the secondary, tertiary and quaternary structure of a polypeptide sequence based solely on the sequence and environmental information? Inverse protein-folding problem: Is it possible to design a polypeptide sequence which will adopt a given structure under certain environmental conditions?
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Protein secondary structure refers to the local conformation proteins' polypeptide backbone. ... Most commonly, the secondary structure prediction problem is formulated as follows: given a protein sequence with amino acids, predict whether each amino acid is in the α-helix (H), β-strand (E), or coil region (C).
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