Is life possible without the presence of rough endoplasmic reticulum?
Answers
because RER helps in the formation of protein.
these proteins are provided by ribosome as well as RER .
therefore yes or no
Endoplasmic reticulum (ER), in biology, a continuous membrane system that forms a series of flattened sacs within the cytoplasm of eukaryotic cells and serves multiple functions, being important particularly in the synthesis, folding, modification, and transport of proteins . All eukaryotic cells contain an endoplasmic reticulum (ER). In animal cells, the ER usually constitutes more than half of the membranous content of the cell. Differences in certain physical and functional characteristics distinguish the two types of ER, known as rough ER and smooth ERRough ER is named for its rough appearance, which is due to the ribosomes attached to its outer (cytoplasmic) surface. Rough ER lies immediately adjacent to the cell nucleus, and its membrane is continuous with the outer membrane of the nuclear envelope. The ribosomes on rough ER specialize in the synthesis of proteins that possess a signal sequence that directs them specifically to the ER for processing. (A number of other proteins in a cell, including those destined for the nucleus and mitochondria, are targeted for synthesis on free ribosomes, or those not attached to the ER membrane; see the article ribosome.) Proteins synthesized by the rough ER have specific final destinations. Some proteins, for example, remain within the ER, whereas others are sent to the Golgi apparatus, which lies next to the ER. Proteins secreted from the Golgi apparatus are directed to lysosomes or to the cell membrane; still others are destined for secretion to the cell exterior. Proteins targeted for transport to the Golgi apparatus are transferred from ribosomes on rough ER into the rough ER lumen, which serves as the site of protein folding, modification, and assembly.