Question

is mRNA material for adhesion of ribosomes​

Answer 1

Answer:

Messenger RNA (mRNA) is a large family of molecules responsible for transferring genetic information stored in DNA to the cell through its translation into functional proteins. The multi-stage “life-cycle” of mRNA—from transcription to translation and degradation—is regulated by a diverse array of RNA binding proteins (RBPs) that influence every aspect of proper and essential gene expression.

Gene expression begins with transcription, the process of creating an mRNA copy of a DNA template. To initiate this process, transcription factors and co-activators bind to DNA gene regulatory elements—promoter regions and enhancer sequences—which signal the recruitment of RNA polymerase II to form the RNA transcription complex. RNA polymerase then separates the strands of the DNA helix and synthesizes a pre-mRNA copy of the template strand by joining complementary RNA nucleotides in a 5’ to 3’ fashion.

During transcription, pre-mRNAs are assembled into ribonucleoprotein (RNP) complexes for editing and processing. These steps, which include 5’ mRNA capping, adenosine to inosine editing, m6A modification, pseudouridylation, splicing, 3’ processing, and polyadenylation, collectively ensure the stability of the mRNA transcript, regulate nuclear export, and promote efficient translation by the ribosome. Each stage requires the association and activity of distinct sets of RBPs and enzymes and is surveilled by nuclear mechanisms to prevent processing errors and safeguard gene expression. Ultimately, these events lead to the production of an export-competent mRNP that translocates through the nuclear pore to the cytoplasm, guided by the interactions of key RBPs, including NXF1, XPO1, and PHAX.

Answer 2

In contrast, the β‐actin mRNA‐binding protein, ZBP1 ... 1977), the movement of ribosomes and mRNA to focal adhesion .