Question

Isoniazid is synthesized from.
O a) alpha picoline O b) beta picoline O c) gamma picoline O d) all of the above ​

Answer 1

Explanation:

Isoniazid can be synthesized in a two-step synthesis out of isonicotinic acid. First isonicotinic acid is turned into isonicotinic- acid-ethylester by an acid-catalyzed esterification with ethanol: At the beginning of the reaction the carbonylgroup is protonated by the acid, so the carbon gets more reactive.

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Answer 2

Answer:

Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis.[2] For active tuberculosis it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol.[3] For latent tuberculosis it is often used by itself.[2] It may also be used for atypical types of mycobacteria, such as M. avium, M. kansasii, and M. xenopi.[2] It is usually taken by mouth but may be used by injection into muscle.[2]

Isoniazid

Isoniazid skeletal.svg

Isoniazid 3d.png

Clinical data

Trade names

Hydra, Hyzyd, Isovit, others

Other names

isonicotinic acid hydrazide, isonicotinyl hydrazine, INHA